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Sinemet wearing off


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#1 michelleee

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Posted 19 July 2011 - 04:29 PM

Hello Doctor,

It's possible I have missed this topic so forgive me if it has already been discussed.

My husband was diagnosed about 10 years ago with PD. He is now 58 years old and is currently taking 25/100 mgs Sinemet every 1 hour and 45 mins.

It's clear now that Sinemet is wearing off faster and faster. My husband has tried all the dopamine agonists out there....with nothing but terrible side effects.

Do we have other options outside of brain surgery?

We have been to three neurologists that seem stumped at this point.

Thank you for you time on this subject.

Michelle Bechtol

#2 Dr. Okun

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Posted 20 July 2011 - 06:32 AM

Moving doses closer, trying liquid sinemet, adjusting dose and considering DBS or duodopa pumps--these are all great options.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips

#3 michelleee

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Posted 22 July 2011 - 01:01 PM

[quote name='Dr. Okun' date='20 July 2011 - 04:32 AM' timestamp='1311161565' post='41170']
Moving doses closer, trying liquid sinemet, adjusting dose and considering DBS or duodopa pumps--these are all great options.
[/quo
Duodopa Pumps? That's the one option that is new to me. Can you point me in the direction that I may find out more.
:grin:
Thank you!
Michelle

#4 Dr. Okun

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Posted 23 July 2011 - 08:45 AM

These are tubes that go into the stomach and pump in continuous doses of dopamine. They are in clinical trials in the USA and already available in Europe.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips

#5 michelleee

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Posted 28 July 2011 - 12:12 PM

These are tubes that go into the stomach and pump in continuous doses of dopamine. They are in clinical trials in the USA and already available in Europe.

Thank you Doctor, I'll check it out.
Best regards,
Michelle

#6 Dr. Okun

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Posted 29 July 2011 - 06:00 AM

Good luck.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips

#7 joaocar29

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Posted 06 August 2011 - 07:00 AM

Thank you Doctor, I'll check it out.
Best regards,
Michelle



#8 joaocar29

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Posted 06 August 2011 - 07:02 AM

Moving doses closer, trying liquid sinemet, adjusting dose and considering DBS or duodopa pumps--these are all great options.






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