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Sinimet ER ineffective

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#1 jwr1952



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Posted 11 December 2012 - 02:17 PM

I take one half of a regular Sinimet (25/100) and 1 Sinimet ER (25/200) six times a day. I also take Requip ER 8mg at bedtime. Sometimes the Sinimet ER just doesn't seem to work. Some days my cycle works fine, on other days I become extremely rigid (difficult to walk even with a walker) at times when my sinimet should be at a high level.

As a test, for two days i ate as little protien as possible. That helped, but did not eliminate the problem.

If i do nothing, I my legs often stay rigid until the next sinimet pill. If I take another half of the regular Sinimet I generally loosen up in half an hour.

I am 60 and was diagnosed with Parkinson's in 2006.

This problem started about two months ago. It is making me reluctant to go to parties or events, becuase i do not know when it will occur.

Can you recommend additional things that I could try?

#2 Dr. Okun

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Posted 11 December 2012 - 05:15 PM

I would see your doc. I would be sure to take your meds at exact times and equally spaced (for example every 3 or 4 hours exactly). I would give your meds a one hour head start before eating. Finally you may want to switch to regular sinemet which has 20% or so more pop. You may simply be undermedicated and need your doc to increase dose. Don't forget physical and occupational therapy.

Michael S. Okun, M.D.

Author of Amazon Kindle, Paperback and Audio of 10 Breakthrough Therapies for Parkinson's Disease
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips

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