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Nausea, esophageal spasms


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#1 Beau's Mom

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Posted 04 January 2013 - 03:59 AM

I've had nausea and constant burping of air for the past nine hours. I have not vomited, but the nausea and retching have gone on for nine hours unabated. and have kept down meds at 6 and 9 PM, including 9 hours. I have kept down 1/2 tab 25/100 carb/levo, 1.5 tabs of 25/100 carb/levo CR at 6 PM, as well as 1 mg clonazepam About 8 PM I was given 4 mg Zofran IM. At 9 PM I took 300 mg of fluvoxamine, 1 mg clonazepam, 200 mg trazadone,10 mg Baclofen, 25 mg of Seroquel, followed one hour later by 2 mg Ativan PO. The nausea is as bad as ever. A medical resident had me take 4 mg Zofran sub-lingual 20 minutes ago. So far no relief. Now my nurse thinks another dose of the two carb levos will put me to sleep. I seriously doubt it. The resident is calling back soon

I have quite a of dysphagia. Could two missed missed doses of 1/2 tab 25/100 between noon and six PM have caused spasms in my esophagus? Since nothing has helped, that's the only theory I have. Please respond ASAP because you will probably answer around 4 AM PST. Thank you.

I am not a human being trying to have a spiritual experience; I am a spiritual being having a (sometimes difficult) human experience.

 

First symptoms: right-hand tremor, constipation and restless arms 1978 (age 25). Depression and anxiety (non-motor symptoms) began in 1989 and worsened through the years. Last inpatient episode June 2013.

Diagnosed December, 2010 by a regular neurologist (age 57). After negative reactions to Requip, Mirapex and selegiline began Sinemet 25/100 3x/day. First MDS visit in Houston in February of 2011 was inconclusive. Second MDS visit at Baylor Fort Worth in May/June 2011 diagnosis changed to Parkinsonism, Sinemet stopped. Third MDS visit in August 2011 in WA State: received a confirmed diagnosis of idiopathic PD which had started on the right side and had now crossed to the left side as well. Restarted on Sinemet 25/100 4x/day. A short trial of Amantadine caused audio hallucinations in September 2011.

 

Current medications at age 62: Sinemet 25/100 ODT every 2.5 hours while awake (7/day). One Sinemet 25/100 CR between midnight and 4 AM. Trazodone 200 mg at bedtime, Fluvoxamine 300 mg at bedtime. Clonazepam 0.5 mg morning and afternoon, 1 mg at bedtime. Vit D3 2x/day, Calcium Carbonate Susp. 5 cc daily, Baclofen 10 mg 3x/day, Flonase two sprays 2x/day, Calcitonin-Salmon nasal spray once daily (for osteoporosis). Gel eye drops as needed throughout the day, Restasis Eye drops 2x/day, Nighttime eye ointment at bedtime. 02 2L per nasal cannula while asleep. Walker, electric wheelchair, moist and soft or pureed foods and 115 caregiver hours/month keep me sane.

 

All of the above subject to change based on progression, stress level, and dyskinesia. Whew! I'm glad I finally wrote that all out.


#2 Dr. Okun

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Posted 04 January 2013 - 08:13 AM

Two other options for nausea are tigan and domperidone.

Usually missing sinemet does not cause spasms, but in some cases could impact swallowing.

You may want to crush the tablets, take the parcopa dissolvable sinemet or ask about a temporary NG tube they can place to get medications down (a tube through the nose into the stomach).

Feel better soon.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
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UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
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or his parkinsonsecrets.com blog for treatment tips

#3 Gerry22

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Posted 21 January 2013 - 02:26 AM

Have you been diagnosed with spasms? I have the same symptoms and I thought it was gastroperesis. I am having esophageal spasms test on 12/13. But gastric emptying tests came back negative. Can you tell me more about your symptoms and what you have been through?


Edited by Gerry22, 11 January 2014 - 01:01 AM.





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