Cigars and Coffee
Posted 11 May 2013 - 07:47 PM
I was wondering if anyone here smokes Cigars or Drinks Coffee? I've been a coffee drinker ever since I joined the US ARMY (Infantry) Back in the 70's and I still do twice a day. I'm also a Cigar smoker and still do occassionally. Cigars and Coffee IMHO has never been an issue even after being diagnosed with PD.
Posted 11 May 2013 - 08:51 PM
Posted 12 May 2013 - 04:15 AM
"We have begun quantitative studies of both acute and chronic nicotine in PD to assess both cognitive and motor effects......Preliminary analysis shows improvements after acute nicotine in several areas of cognitive performance, particularly measures such as reaction time, central processing speed, and decreased tracking error. Improvements in attention and semantic retrieval were not seen. After chronic nicotine, improvements were seen in several motor measures suggesting improved extrapyramidal functioning. This appeared to be sustained for up to 1 month after drug. The treatment was well tolerated. Nicotinic stimulation may have promise for improving both cognitive and motor aspects of Parkinson's disease."
"Both retrospective and prospective epidemiological studies have consistently demonstrated an inverse association between cigarette smoking and PD, leading to theories that smoking in general and nicotine in particular might be neuroprotective. Nicotine has been shown in animals to stimulate the release of dopamine in the striatum, and to preserve nigral neurons and striatal dopamine levels in laboratory animals with lesioned nigrostriatal pathways. Coffee and caffeine consumption have also been shown in epidemiological studies to be inversely related to PD risk. Caffeine is an adenosine A(2A) receptor antagonist that enhances locomotor activity in animal models of parkinsonism. Theophylline, a related compound that has A(2A) receptor blocking properties, has been shown in one small trial to improve motor function in patients with PD. Recently, potent and highly selective A(2A) receptor antagonists have been developed that have demonstrated improvement in motor function in animal models of parkinsonism. Exciting findings are emerging that demonstrate attenuation of dopaminergic neurotoxicity with caffeine and other adenosine receptor antagonists in mice given the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), suggesting that these compounds may be neuroprotective. Evidence for the neuroprotective potential of nicotine and caffeine is compelling, but further work is needed before testing these and related compounds in clinical trials for both individuals at high risk of developing PD and those with early, untreated disease"
Posted 12 May 2013 - 05:27 AM
Nicotine and caffeine are just perfect for PD.
...minus the well known health risks (lung cancer,cardiovascular diseases, etc....) associated with smoking, regardless of parkinson's. I would probably stick with lots of coffee and a cigar every now and then....Until the pharmaceutical industry finds a way to make nicotine-based drugs for parkinson's without the nasty side effects....
Posted 12 May 2013 - 05:44 AM
Posted 12 May 2013 - 02:54 PM
Reading all the studies on nicotine and PD, my personal opinion is that nicotine in a gum or patch form seems to offer PWP a lot of benefit with minimal concern over other health issues.
Posted 12 May 2013 - 03:20 PM
Posted 12 May 2013 - 06:11 PM
Posted 13 May 2013 - 06:58 PM
Smoked a Stogie this past Saturday after working in my back yard. Then had a Padron Cigar after dinner on Mother's Day with an expresso! It was Priceless!! Then rode my Harley Davidson with my Daughter who is on my sig picture here! Everyone tells me that She looks like Me!
Posted 27 May 2013 - 07:31 AM
Edited by Oakman, 27 May 2013 - 07:32 AM.
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