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just started azilect and i'm worse


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#1 soccertese2010

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Posted 24 July 2013 - 07:42 AM

1. am taking only carbidopa/levodopa, avg 800mg/day, get a predictable result but decided to try azilect.
2. day 1 took 0.5mg, felt somewhat different mentally, maybe a little "edgy", blood pressure ok, C/L worked as it always did.
3. day 2 took 0.5mg, waited 30min, took 125 mg of C/L on empty stomach as always and which normally takes affect in 40min and nothing happened.
3 hrs later took another 125mg C/L, no benefit from C/L.
2hrs later took 100mg C/L and 200mg C/L-CR, about 30min later started feeling some affect, took my regular C/L doses the rest of the day but never got the same relief as i normally get from C/L, mentally felt odd.

this morning took no azilect and `125mg C/L, switched on in about 40 minutes as usual.

question, have you seen this before with azilect and if so, should i just give it more of a chance?

i have tried selegilene in the past but stopped it due to ringing in the ears and other side affects but i didn't have this negative affect on C/L.

thanks

#2 Dr. Okun

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Posted 24 July 2013 - 12:49 PM

This is not a common reaction to Azilect but everyone is different. The typical dose is 1mg and I usually try that before giving up. Thanks for sharing your experience!

Michael S. Okun, M.D.

Author of Amazon Kindle and Paperback 10 Breakthrough Therapies for Parkinson's Disease
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips


#3 soccertese2010

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Posted 25 July 2013 - 07:20 AM

so i should start with 1mg?

#4 Dr. Okun

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Posted 25 July 2013 - 01:50 PM

This should be a discussion between you and your doc. In my clinic I usually skip 0.5mg and start at 1mg.

Michael S. Okun, M.D.

Author of Amazon Kindle and Paperback 10 Breakthrough Therapies for Parkinson's Disease
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips





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