Hi Dr., I was diagnosed in 2010 and at this juncture the meds work very well for me. Most people do not even know I have PD on my job. I have a very stressful job and commute public transportation 3 hours each day. I presently take 1 mg Azilect, 6 tabs a day of 25/100 generic sinement, and one Neupro patch 2mg a day. Last new med was Neupro added in about March of this year. Beginning shortly after I started Neupro I started having attacks where I am so nauseous and I feel like I have the flu (without fever or aches) I just feel bad. This comes over me most times when my stomach is empty at the end of day coming home from work. When I get home I have to lay down and rest before I eat. It depends on how bad the attach is as to how much rest I have to have before I eat. Earlier this year, I was the care giver for my mother who was finally committed to a pysch unit and now nursing home. During that period the attacks were really bad. I just had an appointment with my neurologist this past week and she doesn't think it is the Neupro patch because if it made me nauseous the nausea would have been gone by now because I have been on the patch for too long. The attacks don't happen all of the time. If I am stressed out or have overdone it then I definitely get an attack. My Neurologist told me to go to my primary care and get gastro testing. What do you think. I think it is either the Neupro patch or it is just a symptom of PD. A friend at work's aunt has PD and he says she gets sick and can't get out of bed on the days she is sick.