I am taking Sinemet (25/100) and Comtan 3x a day at a 3.5 hour interval, which on a good day reduces my tremor to a fairly consistent, mild level I am comfortable with. I exercise frequently, and I notice that after an intense workout my tremor increases markedly. Others in my support group note the same phenomenon. Does exercise burn the levodopa at a faster rate than it's normally metabolized? If so, can we adjust the medication to anticipate a heavy workout, either adding an extra Sinement or fraction of it or accelerating the next dose (or fraction of it)?