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Does anyone have experience with Mirtazapine to aid with Sleep?


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#1 jbirish

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Posted 24 February 2014 - 12:32 PM

Just wondering if anyone has had any reactions, success, or problems with taking Mirtazapine. My doctor has prescribed the medicine to help me sleep, as I am awake each night with terrible leg cramps and tremors. I am worried because it is an anti-depressant and one of added benefits is as a sleep aid. My doctor assures me there are no adverse symptoms for this medicine with PD.



#2 Beau's Mom

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Posted 24 February 2014 - 05:34 PM

I took Mirtazapine as an antidepressant and it caused significant weight gain, so I had to stop it.


I am not a human being trying to have a spiritual experience; I am a spiritual being having a (sometimes difficult) human experience.

 

First symptoms: right-hand tremor, constipation and restless arms 1978 (age 25). Depression and anxiety (non-motor symptoms) began in 1989 and worsened through the years. Last inpatient episode June 2013.

Diagnosed December, 2010 by a regular neurologist (age 57). After negative reactions to Requip, Mirapex and selegiline began Sinemet 25/100 3x/day. First MDS visit in Houston in February of 2011 was inconclusive. Second MDS visit at Baylor Fort Worth in May/June 2011 diagnosis changed to Parkinsonism, Sinemet stopped. Third MDS visit in August 2011 in WA State: received a confirmed diagnosis of idiopathic PD which had started on the right side and had now crossed to the left side as well. Restarted on Sinemet 25/100 4x/day. A short trial of Amantadine caused audio hallucinations in September 2011.

 

Current medications at age 62: Sinemet 25/100 ODT every 2.5 hours while awake (7/day). One Sinemet 25/100 CR between midnight and 4 AM. Trazodone 200 mg at bedtime, Fluvoxamine 300 mg at bedtime. Clonazepam 0.5 mg morning and afternoon, 1 mg at bedtime. Vit D3 2x/day, Calcium Carbonate Susp. 5 cc daily, Baclofen 10 mg 3x/day, Flonase two sprays 2x/day, Calcitonin-Salmon nasal spray once daily (for osteoporosis). Gel eye drops as needed throughout the day, Restasis Eye drops 2x/day, Nighttime eye ointment at bedtime. 02 2L per nasal cannula while asleep. Walker, electric wheelchair, moist and soft or pureed foods and 115 caregiver hours/month keep me sane.

 

All of the above subject to change based on progression, stress level, and dyskinesia. Whew! I'm glad I finally wrote that all out.


#3 Annikin

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Posted 25 February 2014 - 03:23 PM

I took it- it was the first drug the MDS prescribed. After one dose  I slept for 2 days, woke up feeliing stoned- went hanggliding (yes, hanggliding)- slept all the way home then continued to sleep for another 36 hours!  Even a fraction of the dose knocks me out for way too long.



#4 Beau's Mom

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Posted 26 February 2014 - 10:50 AM

You should probably add Mirtazapine to your drug allergies list, since you are so sensitive to it. I had to do that with another psych drug called Lamictal because within 15 minutes of taking it I couldn't even get myself into bed. Any drug that causes an adverse reaction should be on your drug allergies list. Did you manage to stay awake during the hang gliding? I would hate to miss that experience!


I am not a human being trying to have a spiritual experience; I am a spiritual being having a (sometimes difficult) human experience.

 

First symptoms: right-hand tremor, constipation and restless arms 1978 (age 25). Depression and anxiety (non-motor symptoms) began in 1989 and worsened through the years. Last inpatient episode June 2013.

Diagnosed December, 2010 by a regular neurologist (age 57). After negative reactions to Requip, Mirapex and selegiline began Sinemet 25/100 3x/day. First MDS visit in Houston in February of 2011 was inconclusive. Second MDS visit at Baylor Fort Worth in May/June 2011 diagnosis changed to Parkinsonism, Sinemet stopped. Third MDS visit in August 2011 in WA State: received a confirmed diagnosis of idiopathic PD which had started on the right side and had now crossed to the left side as well. Restarted on Sinemet 25/100 4x/day. A short trial of Amantadine caused audio hallucinations in September 2011.

 

Current medications at age 62: Sinemet 25/100 ODT every 2.5 hours while awake (7/day). One Sinemet 25/100 CR between midnight and 4 AM. Trazodone 200 mg at bedtime, Fluvoxamine 300 mg at bedtime. Clonazepam 0.5 mg morning and afternoon, 1 mg at bedtime. Vit D3 2x/day, Calcium Carbonate Susp. 5 cc daily, Baclofen 10 mg 3x/day, Flonase two sprays 2x/day, Calcitonin-Salmon nasal spray once daily (for osteoporosis). Gel eye drops as needed throughout the day, Restasis Eye drops 2x/day, Nighttime eye ointment at bedtime. 02 2L per nasal cannula while asleep. Walker, electric wheelchair, moist and soft or pureed foods and 115 caregiver hours/month keep me sane.

 

All of the above subject to change based on progression, stress level, and dyskinesia. Whew! I'm glad I finally wrote that all out.


#5 Annikin

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Posted 26 February 2014 - 05:21 PM

Yes and I remembered that part- figured I'd get a jump start  (no pun intended) on my bucket list- it was awesome!! 

 

Sadly I have a very long adverse drug rxn list- as well as things like band aid adhesive, latex, iodine. I am one of those folks who has the rare side effects listed on drug sheets. When I go to the hospital I get three wrist bands. Fortunately my best friend is a nurse who  makes sure someone stays with me whenever a new drug is ordered until I am out of danger.






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