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Should I ask my Doctor about Parkinson's Disease Drug Intervals as well as Dose?


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#1 Dr. Okun

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Posted 21 September 2010 - 12:56 PM

Should I be asking my doctor about the timing of my Parkinson’s disease medication? Does the interval really matter?

We have found through many years of caring for persons with Parkinson’s disease that both patients and practitioners commonly discount the importance of medication timing, choosing instead to focus on specific drugs and particular dosages. This is a correctable mistake, and one that may have important quality of life implications. As your Parkinson’s disease changes over time, so should your medication regimen. Ask your doctor at each visit about adjusting medication intervals as well as dosages. Most patients will need to move beyond three times a day dosing, and ultimately require medications at strict intervals. Such regimens can help to avoid wearing off and other medication related motor complications.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips

#2 gmk

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Posted 24 September 2010 - 06:10 PM

Should I be asking my doctor about the timing of my Parkinson’s disease medication? Does the interval really matter?

We have found through many years of caring for persons with Parkinson’s disease that both patients and practitioners commonly discount the importance of medication timing, choosing instead to focus on specific drugs and particular dosages. This is a correctable mistake, and one that may have important quality of life implications. As your Parkinson’s disease changes over time, so should your medication regimen. Ask your doctor at each visit about adjusting medication intervals as well as dosages. Most patients will need to move beyond three times a day dosing, and ultimately require medications at strict intervals. Such regimens can help to avoid wearing off and other medication related motor complications.


It seems that choosing DOSAGE means both:
1. determining DOSE (how much of medication to take on one occasion) and
2. adjusting medication timing by choosing an adequate time INTERVAL between the doses
(determination how often the dose of medicament is to be taken in 24 hours,
i.e., how much of the medicament is taken daily: DOSE PER DAY).
Now, it would seem that increasing a dose would have the effect of corresponding enlargement of the interval,
but this is not always the case. So, in practice, change in interval tends to take a priority to a change in dose.
First, try a change in interval, then change the dose.

And, if the present dosage results in rather satisfactory response, be careful, do not try to make it even better.
gmk

#3 Dr. Okun

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Posted 25 September 2010 - 11:53 AM

Thanks for the comment.
Michael S. Okun, M.D.
Author of the Amazon Bestseller Parkinson's Treatment: 10 Secrets to a Happier Life
National Medical Director | NPF
UF Center for Movement Disorders & Neurorestoration
Read More about Dr. Okun at: http://movementdisor...hael-s-okun-md/
or Visit Parkinson's Disease treatment and research blogs at:
NPF's What's Hot in Parkinson's disease
or his parkinsonsecrets.com blog for treatment tips




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