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  1. Meds not working

    Wife has been diagnosed via Datscan as less dopamine. Began a regimen of 25/100 simemet 3 per day, also gabapentin 100 mg 5 per day, and was on Amantadine for several weeks at lowest dose twice per day. Now weened off Amantadine and trying to cut back gabapentin, but severe pain in the knee area and swollen ankles have us thinking it may be the Sinemet. Pain has been there through all this regimen and becomes most severe at nighttime. Are meds to blame? ortho exam shows legs normal