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Found 4 results

  1. MurrayPD2

    Problems that repeat

    I am curious about odd behavior I am experiencing. last year, I had a Hypersexuality and ICD issue with Agonists. I immediately quit it one night and never took again The odd part is about a year later, I find myself doing things and I don't know why. It seems irrational. Has anybody ever heard of this?
  2. MurrayPD2

    Problems that repeat

    I am curious about odd behavior I am experiencing. last year, I had a Hypersexuality and ICD issue with Agonists. I immediately quit it one night and never took again The odd part is about a year later, I find myself doing things and I don't know why. It seems irrational. Has anybody ever heard of this?
  3. I have Parkinsons (7 yrs) and take C/L 1.5 tabs of 25/100 4 times per day. Recently, I developed severe leg cramping at night. The MDS ordered Ropinerole .5 mg at bedtime (only.) I initiated it, but had major grogginess the next day. After reducing the dose to .25 mg, I had effective relief and very good sleep without side effects the next day for 6 months. Unfortunately, the leg cramps started to return and I had to increase the dose to .5 mg, again resulting in cumulative fatigue and grogginess the next day. This became unbearable and limited daily function so MDS ordered a change to Pramipexole at .5 mg one month ago. This medication makes it difficult for me to sleep and I get aching in my calf muscles (both sides.) I experienced this in an earlier trial too. My legs act like they are about to cramp again. MDS okayed trial of 1.0 mg 2 hours prior to bedtime. After taking for 2 days, I still have difficulty sleeping and my legs ache at night and want to cramp. I am starting to get groggy in the daytime again too. Since both meds are agonists, I am having difficulty understanding the difference in side effects and direct effects. Without the meds, my legs get severe cramps and I have to get up and take C/L at night to resolve. Sleep is greatly decreased. C/L CR does not work at night as the time frame still wears off during the night. I tried Rytary early on and it really irritated my gut. Do I need to try the Pramipexole a little longer at 1.0 mg or is there another strategy I could try? I liked that Ropinerole puts me to sleep in 15 minutes, but not the grogginess the next day.
  4. There are many reasons to think carefully before allowing your neurologist or MDS to talk you into starting PD drugs. Current PD meds only treat the symptoms, not the disease. Are the benefits worth the side effects? Are the PD meds addictive - do you constantly need more and more to achieve the same result? These issues have often been debated on the forum. However, there is another important thing to consider when faced with the decision to begin taking PD meds. When you take that first does of Sinemet or an agonist, you are eliminating yourself from being able to participate in many of the exciting new clinical trials. That is exactly what happened to me in the Isradipine trial. That 4 months that I took PD meds (Mirapex) eliminated me from the Isradipine trial, even though I stopped Mirapex many months ago. The same will be true of the Inosine trial next year. Take PD meds and you're out! I wish I had never taken that first PD med. The irony is that it was only moderately effective and the side effects were worse than the PD, which is why I stopped.
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