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vietkieu posted a topic in Ask the PharmacistI am 75 and have had Parkinson’s for 14 years and had Beep Brain Stimulation (DBS) in 2012 but am still on high doses of medication being Madopar 125 mg (one and a quarter tablets) 6 times per day, Sifrol ER (pramipexole) 3.75mg once per day, Amantadine 100 mg twice per day to control dyskinesia. Also Mirtazapine 15 mg per day for depression. I have some osteoporosis of left forearm so I take Fosamax 70mg/70 mcg (1 tablet) per week and Caltrate (1500mg calcium carbonate) once per day and Vitamin D 1000 IU liquid once per month. Is it necessary to take all 3 (Fosamax, Caltrate, Vitamin D)? I have been advised to take Fosamax for the rest of my life. When I go to the dentist I take an antibiotic Amoxycillin 500mg 4 capsules (total 2000mg) 1 hour before the appointment and 2 capsules after the appointment to minimize bacteria settling on DBS hardware . For hayfever I occasonally take Claratyne (Loratadine) 10mg. Do all these medications agree with each other is there any contraindication? Am I over-medicated either for Parkinson’s or for osteoporosis?