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  1. I am 75 and have had Parkinson’s for 14 years and had Beep Brain Stimulation (DBS) in 2012 but am still on high doses of medication being Madopar 125 mg (one and a quarter tablets) 6 times per day, Sifrol ER (pramipexole) 3.75mg once per day, Amantadine 100 mg twice per day to control dyskinesia. Also Mirtazapine 15 mg per day for depression. I have some osteoporosis of left forearm so I take Fosamax 70mg/70 mcg (1 tablet) per week and Caltrate (1500mg calcium carbonate) once per day and Vitamin D 1000 IU liquid once per month. Is it necessary to take all 3 (Fosamax, Caltrate, Vitamin D)? I have been advised to take Fosamax for the rest of my life. When I go to the dentist I take an antibiotic Amoxycillin 500mg 4 capsules (total 2000mg) 1 hour before the appointment and 2 capsules after the appointment to minimize bacteria settling on DBS hardware . For hayfever I occasonally take Claratyne (Loratadine) 10mg. Do all these medications agree with each other is there any contraindication? Am I over-medicated either for Parkinson’s or for osteoporosis?