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GeorgeNW posted a topic in Ask the PharmacistWhat is a benefit of starting Requip XL and not sinemet? Right now I am taking azilect 1mg which helps a little with slow movement and stiffness. Tremors are not affected. Reading about side affects and evaluating should I ask MDS to try sinemet first just to see what will be improvement. Is it common to have a success with Requip XL over a long run( year or more ) or it just usual transitional phase to sinemet . I am 38 year old and diagnosed 5 months ago. Need to start meds to keep functioning at work.