helplinedonate
  • Announcements

    • ForumAdmin

      Frequently Asked Questions - Step by step guides

      Do you need assistance registering, logging in, posting, etc? Please visit the all new Frequently Asked Question Forum for step-by-step guides. Click the link below to access these helpful guides. Frequently Asked Questions
    • ForumAdmin

      Recursos Nuevos en Español

      http://www.parkinson.org/ayuda   http://www.parkinson.org/espanol    
    • ForumAdmin

      Línea de Ayuda 1-800-473-4636

      Línea de Ayuda 1-800-473-4636   ¿Qué es la línea de ayuda 1-800-4PD-INFO (473-4636) de la Fundación Nacional de Parkinson? Es un número de teléfono gratuito que ayuda a las personas con la enfermedad de Parkinson, sus familiares, amigos y profesionales de salud, a solucionar diferentes inquietudes.   La línea de ayuda ofrece: Información actualizada Apoyo emocional Referidos a profesionales de salud Recursos comunitarios Amplia variedad de publicaciones gratis    
kholden

Pig cell Parkinson's trial approved

3 posts in this topic

Pig cell Parkinson's trial approved

 

 

 

BRONWYN TORRIE

 

Last updated 12:38 16/11/2012

 

 

Health

Hospital plan 'secrecy' upsets pair Starship Hospital comes of age Plea softens tattoo artist 'Mean' Gene Radical operation for girl's rare illness Mad cow link in hunter's death TV shows credited with fall in pregnancies Forum raises awareness of weight loss surgery Pig cell Parkinson's trial approved Gene discovery in Alzheimer's research Sunbed ban plan for teens, fair skinned

Ethical approval has been granted for researchers to insert pig cells into people's brains in a bid to cure Parkinson's disease.

The process has been tested successfully in rats and monkeys, but never in humans.

Four people suffering from the incurable disease will be recruited to take part in the 18-month trial, which could get under way next year.

Health Minister Tony Ryall gave Living Cell Technologies the go-ahead in October to test the safety and clinical effect of NTCELL in New Zealand.

Brain cells from Auckland Island pigs were used as they could help protect the brain and repair damaged nerve tissue.

Living Cell Technologies chief executive Dr Andrea Grant said the trail was approved by the Health and Disability Ethics Committee, which is part of the Health Ministry.

"We are extremely pleased to have received ethical approval in such an efficient timeframe.''

About 10,000 New Zealanders have Parkinson's, which is the second-most-common neurodegenerative disorder worldwide, after Alzheimer's.

Reduced dopamine levels in the brain lead to symptoms such as tremor, rigidity and slowness of movement.

The effectiveness of current treatments, which focus on dopamine replacement, declines as the disease progresses. There is no way to reverse or slow the degeneration of the brain.

 

WHAT WILL HAPPEN

Brain cells from the disease-free Auckland Island pig herd will be transplanted into a person's brain via a catheter.

When transplanted, the naturally occurring "support" cells may help protect the brain and repair damaged nerve tissue.

The cells will be encapsulated with a substance to prevent rejection.

Living Cell Technologies chief executive Andrea Grant said that unlike previous trials, this one would put a "mixture of different neurons" into the dead part of the brain.

"We're encouraging all of these different cell types to grow back, rather than just one."

Four people will receive the pig cells, which help produce cerebrospinal fluid as well as nerve growth factors. They will be assessed every two weeks.

At six months they will have a brain scan to see if there are any changes at the cellular level.

Clinicians will then decide what to do: another implant, deep brain stimulation or nothing.

This will be followed up by another scan at 12 months.

 

Contact Bronwyn Torrie

Health reporter

Email: bronwyn.torrie@dompost.co.nz

Twitter: @brontorrie

 

 

http://www.stuff.co.nz/national/health/7960154/Pig-cell-Parkinsons-trial-approved

Share this post


Link to post
Share on other sites

I have participated in this trial! Works with amazing results with only one minor side effect ...

 

 

business-man-with-pig-head-thumb9123858.jpg

Share this post


Link to post
Share on other sites