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jakare

The role of anti-inflammatory drugs in PD

5 posts in this topic

    When I take anti-inflammatory drugs(such as nimesulide) to treat non-PD related problems, I feel my PD symptoms improve a litle bit. Specially my "off" periods that present less tremor. Is it a coincidence or is it something like the "amantadine phenomena". Do anti-inflammatories have any tole in PD? Should I take nimesulide regularly? 

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No one knows the answer to this question.  Most of the studies of anti-inflammatories in PD have been looking at risk of developing PD and not symptom improvement.  Certainly some patients report mild benefits, however there are risks to long term use.  In general we don't recommend them long term beyond an aspirin a day unless the primary care doc monitors for other gastrointestinal and kidney effects.

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There has been a lot written on PD risk and tumeric, but not a lot of data on symptomatic benefits.

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I think inflammation is the root of all evil.  Blockage = bad   even flow = good

 

When my mom was taking mobic last year she was moving much better but i took her off it out of fear of ulcers.

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