Jump to content
  • Announcements

    • ForumAdmin

      Frequently Asked Questions - Step by step guides

      Do you need assistance registering, logging in, posting, etc? Please visit the all new Frequently Asked Question Forum for step-by-step guides. Click the link below to access these helpful guides. Frequently Asked Questions
    • ForumAdmin

      Recursos Nuevos en Español

      http://www.parkinson.org/ayuda   http://www.parkinson.org/espanol    
    • ForumAdmin

      Línea de Ayuda 1-800-473-4636

      Línea de Ayuda 1-800-473-4636   ¿Qué es la línea de ayuda 1-800-4PD-INFO (473-4636) de la Fundación Nacional de Parkinson? Es un número de teléfono gratuito que ayuda a las personas con la enfermedad de Parkinson, sus familiares, amigos y profesionales de salud, a solucionar diferentes inquietudes.   La línea de ayuda ofrece: Información actualizada Apoyo emocional Referidos a profesionales de salud Recursos comunitarios Amplia variedad de publicaciones gratis    

sinemet dose timing

Recommended Posts

I was interested in how other dose their sinemet.  I was taking it at 8,12 and 4.  I would have a small something to eat for B(I am one of those who cant take it on an empty stomach with out throwing up) then afer an hour during which time I would drive to work I would take my first dose.(When I got to work)  Lately I dont feel that great driving to work especially in the snow so was considering trying to take it before I leave the house.( I am concerned I might get in an accident.) Dont ask me to describe how I feel b/c I just dont feel right.  Maybe you can understand what I mean.  When others ask me to explain how I feel its hard to do.  For those of you still working what type of schedule do you keep with your sinemet?

Thanks for your input!

Share this post

Link to post
Share on other sites

Hi noah,


In the early days when Sinemet made me nauseous, I would eat a dry cracker when I took it. It helped tremendously, and did not interfere with the absorption of the medication. Protein is usually the culprit that prevents quick absorption because the liver processes protein before it will process Sinemet. 

Share this post

Link to post
Share on other sites


I still work and really try to stick to a routine.


I take half a pill sinemet 25/100 as soon as I wake up, along with .05 mg Azilect, am only.


Most nights I wake up one to two times and also take a half.

Throughout the day I continue a half a pill every 2.5-3hrs. Keeping the doses close so not to have a wear off.


Throw protien in there and sometimes that is an issue. I do eat oatmeal, cereal or toast first thing in the am.

It seems to work for me, for now.

Share this post

Link to post
Share on other sites

I take my sinemet 4 times a day Waiting a hour before any protein helps also to maintain strength of dose.I take it 4 times 1.5,1,1.5 and 1 25/100 sinemet.looking for something to hold me till morning as i still wake up about 3 every morning.

sleep do suggest mirmex or roperial before bed instead of last dose sinemet.

Last night i took a ride in the snow on my new snowmobile. Got about a mile away and got stuck.Had to walk back but I got it out this morning..Even PD didnt stop me but it was a long slow walk.lol

Took the dog for a ride today and she loved it,didnt want to get off.

  • Like 1

Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now