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xaxa

Parkinson's and tic disorder

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Hi dr Okun!

I hope you are well. I would like to know what your thoughts are regarding Parkinsonism and dystonias (mostly OMD & torticolis) in the setting of tic disorder. It would seem that I have an imbalance of dopamine rather than a pure loss of dopamine. Somewhat of a dilema, methinks.... have you seen patients like this get relief after DBS? If so, what was their "target" and why? Thank you for your time and effort, as always.

 

Mary

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PD patients often have dystonia and this has a good chance of improving following DBS if there are not contractures.  The tics I have seen are almost always chidhood onset Tourette syndrome patients who later get PD and we know very little about DBS in these cases but presumably there would be a reasonable chance to help motor and vocal tics.

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Thank you Dr. Okun! So in those patients that had a childhood onset tic disorder that later developed Parkinson's disease, do you know if there was a familial tendency or was it sporadic or both? Any relationship to ALS?

Thanks

ps my 10 year old daughter has Tourette's, my mom has bulbar ALS, and my mother-in-law has Parkinson's, recently diagnosed. Lordy. Lol.

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Usually the tics run in families.  I do not know of a genetic connection between tics, PD and ALS.

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