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AQHA270

Azilect/New generic price increase!

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AQHA270    2

I have been taking Azilect for almost 4 years since my diagnosis in 2013. I am also taking generic Simemet 25/100 CR 4 x day and 12 mg . Ropinerole once/day.   After some tweaking I'm getting the Sinemet CR are down to a pretty good timing provided I don't eat a heavy meal anywhere near my dose or get constipated. My quiestion is......I got approval from my Insurance company to stay with the namebrand Azilect since I'd been on it so long. Hated to switch to a generic and have issues. I went into sticker shock when I went to pick it up at the pharmacy yesterday. Even with my insurance saying Ok it's still $243 !! Generic is $143! Since I've started it it copays have gradually increased from  $25 to $50 and then $75 . Now this!!! I had them give me the generic to see what happens. Even that is a bit pricey. So my question. How benificial is Azilect? Is it worth taking ? i know they say that it can be neuro protective and basically mild symptom relief. If it's not worth taking it would certainly make my med's more affordable. It's the most expensive one I take. Just wanted to know what your opinion was. These drug prices are getting rediculous and it's very frustrating! I was a care giver myself for 30 years as Dental Hygienist. It's discouraging how the insurance companies dictate treatment and medications and it's so very wrong!!!! I'll be anxious to hear your thoughts!

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MComes RPH    182

I completely understand where you are coming from. I am a Pharmacist and a person living with Parkinson's. As far as the Azilect is concerned and whether or not you should take it. That question can only be answered by you. Does the Azilect improve your quality of life? if the answer is yes, then you should probably stay on it. 

When it comes to the pricing of medications when a generic version becomes available is a unique situation. In the case of Azilect, when there are one or maybe two companies producing the generic, you will see that the generic will not be much less then what you have been paying for the Brand name before the generic came out. When the generic does come out you ma see that the brand name medication may now be more expense. This is basically due to the fact that most people will be switching to the generic and the Brand name company will be trying to get the most out of what is left in the Brand name market.

I hope this helps.

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MComes RPH    182

Your best bet is to call the Big Box stores like Walmart, Sam's Club, and Costco first. You do not need to be a member of Sam's Club or Costco to have a prescription filled their. Then call Walgreens, CVS, and Rite Aid. The big box stores buy in such large quantities that they can usually charge a lesser price.

I hope this helps and please keep me posted.

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AQHA270    2

I elected to stay on the generic Azilect but I don't think it's as good as the brand name. I feel more internal tremors inbetween my carbidopa/levodopa 25/100 CR doses.  It's not terrible but I can tell it's not as good. As I think back .....last Jan was when all my medication issues started. I was on brand name Requip ER and doing great with just that and Azilect. Then my insurance changed  and I had to  go on a generic. After experiementing with different manufactures I found  one that was tolerable. That's when I decided to start the cabidopa/levodopa . My Motion Disorders Nurse prescribed the CR version 25/100 and it works great but I feel it's not always consistent. It's usually good in the morning thru early afternoon  but by late  afternoon and evening it starts to wear off. It seems it has a lot do with how much I eat thru the day. And sometimes it takes a long time to kick in and then my next scheduled dose kicks in and I feel like it's too much. She had me try the 50/200 CR and that made me all wound up and felt like I could run a marathon. So back to the 25/100. I just feel as if I could have continued with the brand name Requip that I wouldn't have even needed to start the Carbidopa/Levodopa yet. As it is right now I'm paying $114 for the Ropinerole.ER 12 mg.which is a generic.  and $124 for the generic Azilect. . The insurance I have now will cover a portion of the name brand but it would still be almost $400 for the name brand Requip ER.  I also wonder if since the name brand of both the Requip and Azilect worked so well for me that the name brand Sinemet CR would also be better. I'm seeing a new Motion Disorders Specialist in April so I'm hoping we can find something that is more consistent and also get the most benefit for my money.

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MComes RPH    182

When it comes to brand name versus generic there only has to be one consistent factor, that being that the amount of active ingredient has to be the same in both. The other factors in making the tablet are what usually makes the difference in how long or how fast the medication works.

The generic company may use a different filler. The filler is used to an inactive ingredient that is added to the active ingredient to make it into a tablet.  The other factor that comes into play is how hard the ingredients are pressed together to make a tablet. If they are pressed too hard, the tablet will not break down as quickly. If it is pressed to softly, the tablet will fall apart to quickly. At this point the inactive fillers could also then slow down or speed up the absorption process.

As far as the Brand Name Sinemet working better than the generic, I would have to apply the previous rules to this product as well. I only have come in contact with a few patients who take the name brand Sinemet and that is usually because they say it is an allergic reaction issue with a certain generic brand. If you do notice that the Sinemet seems to work during the day but seems to have a shortened activity at night, you may want to take to the doctor about adding a Regular Sinemet (many call it an Immediate Release Sinemet) about one hour prior to your evening dose of Sinemet CR. This Regular Sinemet has a fast onset of action which takes care of the off time you may experience. This will then carry you over to your next dose of Sinemet CR.

I hope this helps and please keep me posted.

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