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My doctor is switching me from 4x daily CL (25/100) to 4x daily Stalevo 100 as I have developed dystonia symptoms when the CL is wearing off. Is there anything in particular I should know about the Stalevo? Concerns? Thanks.

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The only difference between carbidopa/levodopa and Stalevo is that Stalevo has an extra ingredient called Entacapone, which ha a primary purpose of extending the effects of the carbidopa/levodopa. So many of the side effects of these 2 medications will be similar.

Here are some of the more common side effects that Entacapone:

Urine Discoloration

Diarrhea

A possible decrease or full absence of body movement

Uncontrolled twitching of the extremities ( arms and legs) and face, tongue, and lips

Muscle stiffness or pain

Muscle spasms

I hope this helps and please keep me posted

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Mark-

I'm doing pharmacogentic testing to make sure I've not got any issues metabolizing COMT inhibitors.  Stalevo looks like it's coated- similar to Advil (which has never been a problem).  Are Staleveo white inside?  

This may be a viable alternative to the dye free customs.  Got levodopa, carbidopa, something to give me a bump and no dye. 

Waywrd1

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Yes, I believe that Stalevo is white inside as natural levodopa is a white powder. The only color allergy to be concerned with is that of the coating. They use a red iron oxide in the  coating which may, but rarely, cause an allergic reaction if someone can not tolerate the red dye. 

Also, the coating contains a greater amount of sucrose than "normal" tablets usually do. Patients who have a history of absorption problems with fructose or glucose should let their doctors know this before taking Stalevo.

I hope this helps and please keep me posted

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