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Luke

DatScan questions for those who have had one...

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21 hours ago, MusicMan said:

BUt what if you have a positive DaT, but sinemet doesn't do much of anything?

In that case, atypical degenerative parkinsonism (Parkinson's plus syndrome, such as MSA, PSP or CBD) is a possibility, provided there are also other symptoms/red flags suggestive of these syndromes AND rapid disease progression. Notably, the primary criterion of PD exclusion, i.e. non-response to levodopa, must be confirmed by an experienced MDS. In many cases levodopa doesn't seem to work due to other causes (absorption issues, dose adjustment issues etc. ). When these problems are corrected, the patient responds...

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2 hours ago, christie said:

In that case, atypical degenerative parkinsonism (Parkinson's plus syndrome, such as MSA, PSP or CBD) is a possibility, provided there are also other symptoms/red flags suggestive of these syndromes AND rapid disease progression. Notably, the primary criterion of PD exclusion, i.e. non-response to levodopa, must be confirmed by an experienced MDS. In many cases levodopa doesn't seem to work due to other causes (absorption issues, dose adjustment issues etc. ). When these problems are corrected, the patient responds...

Thanks Christie. My progression is definitely NOT rapid, and I've seen 3 different MDS guys (including Dr Okun), so I suppose it's probably absorption or something else.

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