• Announcements

    • ForumAdmin

      Frequently Asked Questions - Step by step guides

      Do you need assistance registering, logging in, posting, etc? Please visit the all new Frequently Asked Question Forum for step-by-step guides. Click the link below to access these helpful guides. Frequently Asked Questions
    • ForumAdmin

      Recursos Nuevos en Español    
    • ForumAdmin

      Línea de Ayuda 1-800-473-4636

      Línea de Ayuda 1-800-473-4636   ¿Qué es la línea de ayuda 1-800-4PD-INFO (473-4636) de la Fundación Nacional de Parkinson? Es un número de teléfono gratuito que ayuda a las personas con la enfermedad de Parkinson, sus familiares, amigos y profesionales de salud, a solucionar diferentes inquietudes.   La línea de ayuda ofrece: Información actualizada Apoyo emocional Referidos a profesionales de salud Recursos comunitarios Amplia variedad de publicaciones gratis    
Sign in to follow this  
Followers 0

Azilect vs Selegilne

4 posts in this topic

What's the difference between azilect and selegiline? 

Edited by LAD

Share this post

Link to post
Share on other sites


Selective Monoamine Oxidase B (MAO-B) Inhibitor- Monoamine Oxidase Metabolizes Dopamine

Also has some affinity for MAO-A

Usually used in combination with levodopa

Has a food restriction interaction with foods containing Tyramine (wine, aged cheese, cured meats) and can cause a severe spike in blood pressure

Is available in tablet and patch form

One of it's metabolites is a derivative of Amphetamine so it should not be used too close to bedtime

has also been used for depression


Newer than selegiline

Selective MOA-B Inhibitor with no apparent affinity for MAO-A

Used as Monotherapy solely for Parkinson's Disease

There has not been a reported case of any food interaction's as there are with Selegiline

Appears to be Neuroprotective where as Selegiline does not

Does not have an Amphetamine derivative as a metabolite so there is no restriction on time of day dosing

More potent than Selegiline (lesser dose controls symptoms to a greater extent than Selegiline)

Only used for Parkinson's Disease

Less side effects than Selegiline


I hope this helps and please keep me posted

Share this post

Link to post
Share on other sites

If you are considering taking it in tablet form, I would recommend the Azilect due to less side effects and greater efficacy. 

I hope this helps and please keep me posted.

Share this post

Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
Sign in to follow this  
Followers 0