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Rainbow

Azilect (Rasagiline)

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Hello,

My mom is a newly diagnosed PD patient in Turkey. She is on pramipexola(0.375 mg) and zoloft (25 mg). I read some benefits about using Rasagiline in PD patients like delaying the disease and my mom asked her doctor if he recommends Rasagiline(I think the drug name is Azilect in Turkey) for her. He told my mom, he is not recommending at this time because it might interfere with Zoloft. Actually she is on a very low dose Zoloft right now and most PD patients might use antidepressants. At this point, we were wondering what type of antidepressants are common in PD patients that  might have the least drug side effects and not interfere with Rasagiline. We really want to know more about that. If you can help us, we will really appreciate.

Thank you very much for your time!

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There have been thousands of patient experiences with SSRI's like Zoloft mixing with MAO-B's such as selegiline and rasagiline---it is safe.  You can monitor for side effects with your doc but the literature strongly suggests this is ok to mix. MAO-A is dangerous to mix, but not MAO-B in most cases.

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Thank you Doctor Okun! I was going to ask one more question: Is dystonia an illness different than PD? and how is it diagnosed? Is there a special test? Just wondering maybe my mom has dystonia.Thanks again.

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This is tricky.  Dystonia can occur as a separate diagnosis, but more people usually have dystonia as part of their PD (curling toes, tilted neck, turned foot, etc.).

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