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How do you decide whether to start with an agonist or Carbidopa-levodopa? I was diagnosed 1.5 yrs ago and am 55 with primarily motor symptoms (no tremor.)  My MDS recommended I start taking something, and she said it is up to me which drug I start with. So why would I take one over the other? HOw do you decide?

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This is a tricky question as there is no right answer.  If you start with an agonist monitor for impulse control and have a family member observe you and report to the doc.  Many people now start with Sinemet or Madopar without issue.  Some people prefer Sinemet if over the age of 70 but there are no hard and fast rules.  Whatever you choose, monitor the symptoms and adjust slowly.

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