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Superdecooper

Azilect drug interaction?

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Hi Mark,

I’m taking CIPRODEX®  (CIPROFLOXACIN AND DEXAMETHASONE) ANTIBIOTIC EAR drops for a swimmers ear infection. I’m also taking 1 mg of Azilect each morning.  Should I be worried about a drug interaction?

-S

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Those are absolutely fine to use together.

I hope this helps and please keep me posted

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So no problem with this warning in the Azilect drug information...

5.4 Ciprofloxacin or Other CYP1A2 Inhibitors 

Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors. Patients taking concomitant ciprofloxacin or other CYP1A2 inhibitors should not exceed a dose of AZILECT 0.5 mg once daily [see Dosage and Administration (2.2)Drug Interactions (7.6), and Clinical Pharmacology (12.3)].

 

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That is only is it is taken orally. The eye drops work topical and do not get absorbed into the blood stream.

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