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Abernard

Namzaric

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Is there a severe drug interaction between Namzaric and Seroquel.

My Mom was just prescribed seroquel and I am wondering how long between the seroquel and Namzaric should I administer it.

The doctor just prescribed my mom the lowest dose of seroquel, I am hesitant to start her on this.

your opinion is much appreciated ! 

 

 

 

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Abernard,

There is a non-severe drug interaction between Namzaric and Seroquel.

Namzaric is made up of two different ingredients, Donepezil and Memantine.

Seroquel can reruce the effectiveness of Donepezil. This interaction may also cause lethergy, confusion, and drowsiness.

Seroquel can also interact with the other ingredient in Namzaric, Memantine. The resulting interaction can range from dry skin, mouth and eyes, to memory loss, confusion, hyperactivity, hallucinations, and twitching or jerking. This is usually more prominent and severe in elderly patients.

This best way to avoid this interaction is to separate taking the medications by at least 2 hours. It does not matter the order in which they are taken, but the separation of 2 hours will allow one medication to be absorbed and metabolised before the other medication is taken.

I hope this helps and please keep me posted.

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Thank you ! My mom is 83 years old and has been on these meds for two weeks and it has helped with her delusions, However, I give her the seroquel 25 mg at 430 pm , namzaric at 6:00 pm and then pretty much she is in a coma like state until 430 in the morning.

she is awake and refreshed and alert, however from what you said above is her dementia likely to get worse ? Is there something else that is less interactive with seroquel. 

You are a blessing !! 

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AB,

More than likely dementia does progress over time. Some patients may have a slower progression than others and medication has been shown to slow the progression and severity of symptoms.

Unfortunately there is nothing for Dementia that will interact less with Seroquel. The two ingredients in Namzaric are also available by themselves and account for the 2 major medications used for Dementia. 

Lowering the dose of Seroquel may help with the severity of the side effects the interaction causes. Another way to decrease the intensity of the side effects is to separate the medications by a greater amount of time. An idea may be to give the Seroquel at 4:00pm and give the Namzaric at bedtime. This way she will be able to stay awake longer but still get a good night's sleep.

I hope this helps and please keep me posted.

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