helplinedonate
  • Announcements

    • ForumAdmin

      Frequently Asked Questions - Step by step guides

      Do you need assistance registering, logging in, posting, etc? Please visit the all new Frequently Asked Question Forum for step-by-step guides. Click the link below to access these helpful guides. Frequently Asked Questions
    • ForumAdmin

      Recursos Nuevos en Español

      http://www.parkinson.org/ayuda   http://www.parkinson.org/espanol    
    • ForumAdmin

      Línea de Ayuda 1-800-473-4636

      Línea de Ayuda 1-800-473-4636   ¿Qué es la línea de ayuda 1-800-4PD-INFO (473-4636) de la Fundación Nacional de Parkinson? Es un número de teléfono gratuito que ayuda a las personas con la enfermedad de Parkinson, sus familiares, amigos y profesionales de salud, a solucionar diferentes inquietudes.   La línea de ayuda ofrece: Información actualizada Apoyo emocional Referidos a profesionales de salud Recursos comunitarios Amplia variedad de publicaciones gratis    
Sign in to follow this  
Followers 0
Dr. Okun

Post of the Week: 3 Symptoms that Precede the Diagnosis of PD

15 posts in this topic

Dear Forum Members,

 

Last week at the World Parkinson Congress in Scotland there was a lot of discussion about symptoms that precede the diagnosis of PD.

 

Three of these discussed included olfaction (smell) which may precede by less than 5 years, REM sleep disorder (acting out your dreams and vivid dreams) which may precede by 10-12 years, and constipation which is less studied in terms of lead time.

 

The identification of early indicators of PD will be important for the field once we have disease modifying therapies.

 

We will keep you posted.

Share this post


Link to post
Share on other sites

Dear Forum Members,

 

Last week at the World Parkinson Congress in Scotland there was a lot of discussion about symptoms that precede the diagnosis of PD.

 

Three of these discussed included olfaction (smell) which may precede by less than 5 years, REM sleep disorder (acting out your dreams and vivid dreams) which may precede by 10-12 years, and constipation which is less studied in terms of lead time.

 

The identification of early indicators of PD will be important for the field once we have disease modifying therapies.

 

We will keep you posted.

Unexpected and repeated FALL/S + ev. with a complication, such as fracture, especially, in a person (Age 50+), "anxiety"-on-exertion,

"depression", trouble with urination, not just the constipation may be early indicator/s preceeding diagnosis of PDs.

gmk

Share this post


Link to post
Share on other sites

Thanks for the post.

 

Early falls preceding the diagnosis may be a sign of another syndrome (PSP, etc.).

 

Certainly anxiety and depression can be the first symptom.

 

I am unaware of early urinary incontinence being an issue, but certainly I have heard changes in urinary frequency and pattern. Early incontinence may also herald Normal Pressure Hydrocephalus.

 

Again, thanks for the great comments on early presentations.

Share this post


Link to post
Share on other sites

Emily,

 

Yes studies have shown certain smells are more commonly affected early in PD.

 

Banana, Licorice, and Dill Pickle are the early smells that may be affected.

Share this post


Link to post
Share on other sites

Dr. Okun,

 

I'm curious about my situation regarding smells. Since being diagnosed with Parkinsons my sense of smell has become more acute. Some smells appear to me to be so strong they become almost nauseating. Another curious thing is that it seems like my brain remembers smells that are no longer present. For example, I'll be driving and get behind a vehicle emitting a strong exhaust odor, like a diesel engine. For almost 10 min. after the vehicle is gone I can still smell the diesel. It happens with other things also. Are either of these situations known to exist with Parkinsons people?

 

Thanks,

Randy

Share this post


Link to post
Share on other sites

Very interesting Randy. I will post for you. I have not heard about this effect, but anything is possible. In some neurological aliments one sense may become sharper.

Share this post


Link to post
Share on other sites

Emily,

 

Yes studies have shown certain smells are more commonly affected early in PD.

 

Banana, Licorice, and Dill Pickle are the early smells that may be affected.

 

There is a ritual that religeous Jews perform every Saturday night at the end of the Sabbath that involves in one part the smelling of certain spices. Cloves are generally one of the spices. For quite a while I kept telling my wife to make sure the clove container is tightly shut so as they should not lose their odor so quickly. I did not realize it was my sense of smell that was playing games. This was at least a year prior to my being diagnnosed with PD.

Share this post


Link to post
Share on other sites

Dear Forum Members,

 

Last week at the World Parkinson Congress in Scotland there was a lot of discussion about symptoms that precede the diagnosis of PD.

 

Three of these discussed included olfaction (smell) which may precede by less than 5 years, REM sleep disorder (acting out your dreams and vivid dreams) which may precede by 10-12 years, and constipation which is less studied in terms of lead time.

 

The identification of early indicators of PD will be important for the field once we have disease modifying therapies.

 

We will keep you posted.

If a symptom/sign qualifies for one preceeding the diagnosis of PD, criteria should be set and first of them would be that it improves with therapy,

specifically, it is L-DOPA responsive.

gmk

Share this post


Link to post
Share on other sites

gmk

 

Diagnosis and treatment should be kept separate. Some symptoms respond to therapy and some do not. Now, you can classify in an individual patient which symptoms respond over time....but for diagnosis I would not recommend using symptom responsiveness for every PD symptom.

 

Thanks for the thoughtful comment.

Share this post


Link to post
Share on other sites

Dr. Okun,

 

I'm curious about my situation regarding smells. Since being diagnosed with Parkinsons my sense of smell has become more acute. Some smells appear to me to be so strong they become almost nauseating. Another curious thing is that it seems like my brain remembers smells that are no longer present. For example, I'll be driving and get behind a vehicle emitting a strong exhaust odor, like a diesel engine. For almost 10 min. after the vehicle is gone I can still smell the diesel. It happens with other things also. Are either of these situations known to exist with Parkinsons people?

 

Thanks,

Randy

 

 

Randy,

 

What you described is the same for me. My sense of smell is more acute, also. I can smell things that no one around me can smell and I also smell odors for a longer period of time like you explained with the diesel. I've had this "extrasensory smell thing" going on for several years.

Interesting...

 

Tonya

Share this post


Link to post
Share on other sites

Really interesting. I will post to see if others have experienced the same thing!

Share this post


Link to post
Share on other sites

Randy,

 

What you described is the same for me. My sense of smell is more acute, also. I can smell things that no one around me can smell and I also smell odors for a longer period of time like you explained with the diesel. I've had this "extrasensory smell thing" going on for several years.

Interesting...

 

Tonya

 

Hi Texas T,

 

I wondered if anyone else shared this experience or if I was just a "weird" one. If two of us have the same thing I'd imagine there are others. It's an interesting sensation, sometimes a bit annoying.

 

Randy

Share this post


Link to post
Share on other sites

I asked a smell expert in PD (a researcher) and he has seen many patients but not heard of this in PD except for smell hallucinations.....which it doesn't sound like that at all.

 

This is very interesting.

Share this post


Link to post
Share on other sites
Sign in to follow this  
Followers 0