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Dr. Okun

New Study: What are the most cited paper's in Parkinson's disease

3 posts in this topic

Dear forum members,

 

These authors recently published a paper examining the papers that have received the most citations in PD (been referred to by other people in PD when they write about PD).

 

Mov Disord. 2010 Nov 10. [Epub ahead of print]

The most cited works in Parkinson's disease.

Ponce FA, Lozano AM.

 

Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.

Abstract

The number of citations a work has received is a measure of its impact. We identified the top cited works in Parkinson's disease. A Web of Science search was performed for articles including the keyword "Parkinson*" in the title (the asterisk was included in the search string as a wild card character). Articles with more than 400 citations, the threshold to be considered a "citation classic," were identified and analyzed. The 107 articles identified appeared in 33 different journals, with clinical articles primarily appearing in the New England Journal of Medicine and Lancet, and scientific articles primarily in Nature, Science, and the Proceedings of the National Academy of Sciences. There were 52 laboratory studies, 38 clinical studies, 12 review articles, and 5 classifications of disease. The clinical studies included evaluation of medical and surgical therapies, and the laboratory studies included gene discovery, molecular biology, and cellular biology, as well as animal models and neuropathological studies. High impact topics included deep brain stimulation, levodopa therapy and related adverse effects, MPTP-based animal studies, discovery and evaluation of genetic mutations, and pathogenesis related to oxidative degeneration. More than half of the articles identified in this study have been published in the past 20 years. Prior to 1990, highly cited articles in Parkinson's disease tended to be those that evaluated medical therapies and defined the clinical and neuropathological characteristics of the disease. Since 1990, a high proportion of the citation classics address the genetic characterization of and surgical treatments for the disease suggesting that these are the most significant recent developments and main drivers of impact in this field. © 2010 Movement Disorder Society.

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I saw a post from another source about a new study regarding the effiveness of Smilagenin (Cogane is the trade name) as a neuro protector. I wrote to the PI and one of the PhD staff wrote back and I have some references, PDF files. I would be very interested in an informed reading the material regarding experiments with Sprague-Dawley being the experimental animal. Is there an email address where I could send these articles? Mine is mmery@horizoncable.com. The studies cited, and the new one starting, look very interesting to me. thanks.

 

Michael Mery

 

 

Dear forum members,

 

These authors recently published a paper examining the papers that have received the most citations in PD (been referred to by other people in PD when they write about PD).

 

Mov Disord. 2010 Nov 10. [Epub ahead of print]

The most cited works in Parkinson's disease.

Ponce FA, Lozano AM.

 

Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.

Abstract

The number of citations a work has received is a measure of its impact. We identified the top cited works in Parkinson's disease. A Web of Science search was performed for articles including the keyword "Parkinson*" in the title (the asterisk was included in the search string as a wild card character). Articles with more than 400 citations, the threshold to be considered a "citation classic," were identified and analyzed. The 107 articles identified appeared in 33 different journals, with clinical articles primarily appearing in the New England Journal of Medicine and Lancet, and scientific articles primarily in Nature, Science, and the Proceedings of the National Academy of Sciences. There were 52 laboratory studies, 38 clinical studies, 12 review articles, and 5 classifications of disease. The clinical studies included evaluation of medical and surgical therapies, and the laboratory studies included gene discovery, molecular biology, and cellular biology, as well as animal models and neuropathological studies. High impact topics included deep brain stimulation, levodopa therapy and related adverse effects, MPTP-based animal studies, discovery and evaluation of genetic mutations, and pathogenesis related to oxidative degeneration. More than half of the articles identified in this study have been published in the past 20 years. Prior to 1990, highly cited articles in Parkinson's disease tended to be those that evaluated medical therapies and defined the clinical and neuropathological characteristics of the disease. Since 1990, a high proportion of the citation classics address the genetic characterization of and surgical treatments for the disease suggesting that these are the most significant recent developments and main drivers of impact in this field. © 2010 Movement Disorder Society.

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You can mail it hard copy to the National Parkinson Foundation or to the Research Director, Ariel Deutsch for NPF who is at Vanderbilt and in the Department of Psychiatry there. Ariel would be a great person to comment on animal models.

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