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Dr. Okun

Post of the Week: Osteoporosis and Parkinson's Disease

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Dear forum members,


Study after study has shown consistent results for bone studies in Parkinson's disease. The bone mineral density in both men and women is reduced, and with weaker bones and an increased fall risk-- we have to worry about fractures. Be sure you are getting bone mineral density testing and keeping your bones as healthy as possible. Here is the abstract from a recent review.



Clin Cases Miner Bone Metab. 2011 Sep;8(3):16-8.

Osteoporosis and Parkinson's disease.

Raglione LM, Sorbi S, Nacmias B.


Department of Neurological and Psychiatric Science, University of Florence, Careggi Hospital, Italy.


Parkinson's disease (PD) and osteoporosis are two conditions with a quite high prevalence in older people. From the literature we learn that in parkinsonian people there a is e major reduction of Bone Mass Density (BMD) compared to age-matched controls. A low BMD is one of the factors related to fracture's frequency in PD patients besides an increased risk of falls. From the standpoint pathophysiology, various factors are involved in osteoporosis: immobilization, endocrine factors like hypovitaminosis D, nutritional and iatrogenic factors.Considering morbidity and mortality related to fractures in old people and in particular in PD patients it is reasonable that these patients would undergo to vitamin and BMD measuring, to fall risk assessment and that all preventive measure are implemented to reduce the risk of fractures. Possible interventions are essentially based on fall prevention and treatment of osteoporosis. Randomized clinical studies in the literature, in which it was studied the effect of anti-osteoporotic drugs in patients with MP showed a significant reduction in the number of fractures and increase BMD.

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